Pennsaid bụ NSAID ngwọta nke nwetara FDA nkwado na November 4, 2009, iji mesoo ihe mgbu na mgbaàmà metụtara ikpere ogbu na nkwonkwo . Aha njirimara maka Pennsaid bụ diclofenac sodium. Nyocha nke Nuvo Research Inc. mepụtara Pennsaid. Nke a bụ mbipụta nke diclofenac, bụkwa nke dị ka mkpụrụ ọgwụ.
Kedu ka Ọrụ Pennsaid si arụ ọrụ?
Ihe ọ bụla na-abụghị steroidal anti-inflammatory drugs (NSAIDs) na-arụ ọrụ site na usoro yiri.
Ha na-egbochi cyclooxygenase, enzyme bụ maka mmepụta nke prostaglandins, nke bụ isi ihe ndị ọrụ ọjọọ na-eme ka ọ bụrụ ihe na-egbuke egbuke. Site na igbochi enzyme ahụ, NSAID na-eduga n'ọtụtụ dị njọ nke prostaglandins ma si otú ahụ na-erughị ncha. N'ụzọ dị mwute, prostaglandins na-enye aka na ọrụ ndị ọzọ nke ahụ, ya mere, NSAIDs nwere mmetụta dị egwu. N'ụzọ dị mkpa, prostaglandins bụ isi n'ime mmepụta akpụkpọ anụ mucous nke afọ nke dị mkpa iji chebe afo imechi mmiri. NSAIDs, site na-ebelata ịda mbà, na-eduga nkwụsịtụ nke mgbochi nchebe a ma nwee ike ịkpata iwe na ọnya afọ.
Nzuzo a na-eji NSAID bụ isi bụ na ngwa ngwa mpaghara nke iji ọgwụ ọjọọ eme ihe ga-eduga n 'okpukpu, na mkpokọta njikọta na mgbu na saịtị nke ngwa, mana ọgwụ ahụ agaghị eru oke mgbatị ọbara iji duga mmetụta ndị nwere usoro dị ka ọnya afọ.
N'eziokwu, ọmụmụ ihe egosiwo na ngwa ngwa nke NSAID usoro nke usoro ọgwụgwọ ahụ bụ nanị ihe dịka pasent 5 nke ihe ha dị n'ime anụ ahụ ebe e ji ọgwụ ahụ eme ihe.
Mmetụta Ọdachi Dịka NSAID
Iji NSAID na-eme ihe na ọgwụgwọ ikpere ụkwụ nke osteoarthritis na-enye ndị nwere ọrịa ụfọdụ ohere ịba uru gastrointestinal.
Usoro a n'azụ uru ndị a dịka akọwapụtara n'elu. Ngwọta nke ebe obibi nwere ike ịdị ize ndụ karịa ka ọ bụrụ na e jiri ya tụnyere NSAID.
Enwere ike maka mmejọ ndị dị ka ọnya afọ , ọbara ọgbụgba na-egbu ọbara , ọrịa izere obi na-adịkwa, ma ọ dị ntakịrị iji tụnyere ụdị ọgwụ ọgwụ ndị a.
Ihe mmetụta kachasị emetụta ya na Pennsaid bụ ịdị nwayọọ ma ọ bụ mgbakasị ebe ọ na-etinye ya n'ọrụ.
Ọ Na-arụ Ọrụ?
Nnyocha a na-adịbeghị anya site na Cochrane Collaboration elelere ọmụmụ ọmụmụ 61 nke nyochara ma NSAID dị elu. Na nkenke, azịza ya bụ ee. Mgbe ha jikọtara data sitere na ọmụmụ ihe niile, ihe dịka pasent 75 n'ime ndị mmadụ nwere ahụhụ dị ukwuu maka mgbu ahụ / nkwonkwo (ihe enyemaka dị oke mkpa dịka ụda nke mgbu ọkara) mgbe ị na-eji diclofenac topical, nke a dị iche na ihe dị ka pasent 50 nke ndị mmadụ nwetara placebo.
Isi mmalite:
Nyocha nke Cochrane nke NSAID
> http://www.cochrane.org/CD007402/SYMPT_topical-non-steroidal-anti-inflammatory-drugs-for-acute-musculoskeletal-pain-in-adults
FDA kwadoro Pennsaid. Drugs.com.
http://www.drugs.com/newdrugs/fda-approves-pennsaid-topical-solution-1758.html
Nke a. NUVO