Beta Amyloid Protein, Plaque, na Alzheimer

Beta-amyloid protein na ihe ncheta - ndị a bụ okwu abụọ metụtara ụbụrụ na-agbanwe n'ọrịa Alzheimer. Chọrọ ịmatakwu ihe? Nke a bụ eziokwu 9 maka gị:

1. A na-eleba anya na ụbụrụ beta-amyloid n'ime ụbụrụ dịka otu n'ime njirimara nke ọrịa Alzheimer . (Ihe ọzọ bụ isi dị mkpa bụ ihe ntanetụ ndị na-adịghị edozi .) Ndị na-edozi protein beta-amyloid na-ejikọta ọnụ iji mee ka a ghara ịkụnye ya (na-enweghị ike ịgbari) plaques n'èzí nke neurons.

1. Ndị na-edozi protein Beta-amyloid na- ewulitekwa na synapses ma na-egbochi nkwurịta okwu site n'otu cell gaa na onye ọzọ na ụbụrụ.
2. Tupu ụyọkọ nke beta-amyloid buru oke ibu nke a na-akpọ ihe akara , ndị na-edozi ahụ na-amalite ụdị oligomers . Ndị na-enye Oligomers ka na-agbazekwa (enwere ike ịgbasa), obere ìgwè nke beta-amyloid.
3. Ọ bụ ezie na a chọpụtalarị ihe dịka otu n'ime ihe ndị kpatara Alzheimer, ndị na-eme nchọpụta akpọwo ajụjụ a n'oge na-adịbeghị anya, na-achọpụta ndị oligomers ndị a kọwara n'elu dị ka eleghi anya ọ bụ otu n'ime ndị isi na-egbochi nkwurịta okwu site na cell gaa cell. Otu ihe kpatara nke a bụ na ụfọdụ ndị nwere ihe nrụpụta n'elu ụbụrụ, ma enweghi ihe mgbaàmà nke ọrịa Alzheimer .
4. Tụkwasị na nke ahụ, nchọpụta ndị ọzọ egosila na mgbanwe mgbanwe na-amalite n'ihu ndị na-edozi protein beta-amyloid site na nnukwu akara akwa.
5. Sayensị chọtara ndị na-edozi protein beta-amyloid karịa 100 afọ gara aga. Dr. Alois Alzheimer nke mbụ mara ha na 1906.

1. Beta-amyloid bụ akụkụ nke protein a na-akpọ amyloid precursor protein .
2. Mmasị ndị na-akpali mmasị: "Ọtụtụ ndị ọkà mmụta sayensị na-echekwa na ihe eji eme ihe n'eziokwu nwere ike ịbụ ụbụrụ nwa oge iji mee ka beta-amyloid a na-adịghị emerụ ahụ" (Ụlọ Ọrụ Ọrịa Na-ahụ Maka Ọrịa Alzheimer).
3. Nnyocha e mere na UC Davis Alzheimer's Disease Center chọpụtara na usoro ahụ ji alụso ọrịa ọgụ meghachiri otu ụzọ ahụ na-egosi nje bacteria, na-ebute ụfụ na ụbụrụ nke mebiri emebi. Ufuru na ụbụrụ ejikọtara ya na ọrịa Alzheimer.

Isi mmalite:

_{Òtù Alzheimer. Ọrịa Alzheimer na-echepụta Beta-Amyloid na "Amyloid Hypothesis." 2008.}

_{Òtù Alzheimer. More About Plaques.}

_{DANA Foundation. Amyloid-Beta 'Ndị Oligomers' nwere ike isonyere Mmehie nke Alzheimer. July 12, 2010.}

_{National Institute of Age. Ụlọ Ọrụ Nkụzi na Ntuziaka Alzheimer nke Ọrịa Alzheimer. Jenụwarị 22, 2015.}

_{Medicinal Stanford. Ndị ọkà mmụta sayensị na-ekpughe otú beta-amyloid nwere ike isi kpatara Alzheimer. September 2013.}

_{UC Davis Health System. Ọkụ Alzheimer na-eme ka Amyloid na bacteria na-ebute Otu Azịza Na-adịghị.}