Nkpọrọgwụ bụ mmiri vitamin soluble mmiri, B-dị mgbagwoju anya nke dị mkpa maka ahụ maka ọtụtụ ọrụ gụnyere ịmepụta sel ọhụrụ ma mee ka ọbara ọbara ọbara.
A na-akpọ ya folate mgbe a na-achọta ya na nri, dịka nchịkwa, mkpụrụ osisi, na akwụkwọ nri akwụkwọ ndụ akwụkwọ ndụ. Folic acid bụ ụdị ihe eji emepụta ihe dị iche iche nke a na - achọta n'ọtụtụ nri siri ike (dịka nri na ọka) na dịka mgbakwunye.
Ndị nwere ọrịa obi na-efe efe (IBD) bụ ndị na- arịa ọrịa na- afụ ụfụ bụ ndị nwere ihe ize ndụ maka enweghị erughị ala, karịsịa ndị na-ewere usoro ma ọ bụ sulfasalazine .
Ihe mere o ji di mkpa
Ahụ apụghị ime fatịlaịza ma ọ bụ folic acid, ya mere ọ ghaghị inweta ya site na nri na ihe mgbakwunye. Ntucha bụ vitamin B nke dị mkpa tupu na mgbe ọ dị ime n'ihi na eji ya n'ime ihe ndị e kere eke na nkewa. Ekwesiri iji ihe ozo na-eme ihe iji gbochie mmebi ngwongwo neural dika nke spina bifida na nwa.
Ọkpụkpụ dị mkpa maka ahụ iji nọgide na-enwe usoro kwesịrị ekwesị nke amino acid homocysteine, bụ nke ahụ dị mkpa maka njikọ protein. Enweghị oke ntụpọ, homocysteine ga-ewuli elu na ahụ. A na-ejikọ ọrịa dị elu nke homocysteine na ọrịa obi.
Ntọhapụ pụkwara inyere aka gbochie ọrịa kansa site na igbochi ụfọdụ mgbanwe na DNA ahụ. Ebe ọ bụ na ọ dị mkpa ịkpụzi ikuku iji mepụta mkpụrụ ndụ ọbara uhie, ịnweta oke nkpuchi dị oke mkpa iji gbochie anemia .
Ihe kpatara ndị ọrịa IBD ji enwe Nsogbu maka Ịkwụsị Ụkọ
Ndị nwere ọrịa Crohn na obere eriri afọ ha nọ n'ihe ize ndụ nke ịba ọrịa ọtụtụ vitamin na mineral-folate gụnyere. A na-etinye uche na etiti na akụkụ ikpeazụ nke obere eriri afọ, jejunum na ileum.
Sulfasalazine na methotrexate bụ ọgwụ abụọ eji agwọ IBD nke nwere ike igbochi metabolism nke folate.
Ihe ndị ọzọ kpatara itinye aka na nsị na-agụnye ịṅụbiga mmanya ókè, ọrịa imeju, na ọgwụ ọgwụ, metformin , triamterene, ma ọ bụ barbituates.
Ọ Bụ Onye ọ bụla nwere IBD na Nsogbu Maka Ọdịda Mbelata?
Otu nnyocha gosiri na ndị ọkachamara na-arịa ọrịa na-arịa ọrịa na-arịa ọrịa dị elu karịa ụmụaka ndị na-enweghị IBD. O juru ndị edemede ahụ anya, ebe ọ bụ na a chọpụtala na a ghaghị imezi n'etiti ndị okenye IBD. E nwere ike iji nlezianya nyochaa ọkwa nke ụmụaka na IBD iji chọpụta ma ọ bụrụ na mkpa dị mkpa n'ezie.
Ndị ọrịa IBD nọ n'ihe ize ndụ maka elu ogo homocysteine. Homocysteine bụ amino acid, na ọkwa dị oke elu na-ejikọta mkpịsị ọbara na mmetụ obi. N'ebe ndị mmadụ na IBD nọ, enweghi ike ime ka ọ ghara ịta ụta n'ihi homocysteine dị elu-ihe àmà na-esemokwu. Ọ dịkarịa ala otu nnyocha e mere egosiwo na homocysteine ga-arịwanye elu na ndị nwere IBD nwere ike ịbụ n'ihi nsonaazụ nke vitamin B12, karịa obere ọkwa nke folate.
Ihe Ị Pụrụ Ime
Iji gbochie erughi ala, enwere ike ịkwado ya na ndị mmadụ na IBD na-eji mgbakwunye folic acid. Ndị na-eburu sulfasalazine na ụkpụrụ, karịsịa, nwere ike ịchọrọ ndị ọzọ folic acid. Achịkọ folic acid nke 1000 micrograms (1 milligram) kwa ụbọchị na-atụ aro maka ndị kasị nọrọ n'ihe ize ndụ nke enweghị isi.
Lelee ya na dọkịta gị iji chọpụta ụdị folic acid ị chọrọ kwa ụbọchị nakwa ma ị ga-ewe ihe mgbakwunye.
Ihe oriri ndị nwere efere ma ọ bụ folic acid bụ:
- Asparagus
- Azụ anụ
- Brọkọlị
- Cowpeas
- Mkpụrụ ọka, osikapa, akwa akwa, na achịcha
- Great Northern agwa
- Green peas
- Akwụkwọ nri
Isi mmalite:
Crohn's na Colitis Foundation nke America. "Nri na Nri." CCFA.org 29 Apr 2009.
Erwan Y, Uzun H, Celik AF, Aydin S, Dirican A, Uzunismail H. "Hyperhomocysteinemia na ọrịa ndị na-arịa ụfụfụ na-egbu egbu nke na-arịaghị ọrịa ọgbụgba gara aga: njikọta na cobalamin, pyridoxine, concentres concentrations, reactants nnukwu, ọrụ ọrịa, na nsogbu nsogbu thromboembolic . " J Clin Gastroenterol 2008 May-Jun; 42: 481-486.
Heyman MB, Garnett EA, Shaikh N, et al. "Uche dị iche iche na-arịa ọrịa na-arịa ọrịa na-arịa ọrịa ụmụaka. Am J Clin Nutr 2009 Feb; 89: 545-550.
Office of Supplements Supplements. "Akwụkwọ Mpempe Akwụkwọ Nri Dietary: Ntọhapụ." National Institutes of Health 15 Apr 2009.
Romagnuolo J, Fedorak RN, Dias VC, Bamforth F, Teltscher M. "Hyperhomocysteinemia na ọrịa obi ụfụ na-egbu egbu: ndị na-ahụkarị na ndị na-ebu amụma na ọmụmụ ihe." Am J Gastroenterol 2001 Jul; 96: 2143-2149.
Akara ML. "Mmetụta nri na antioxidants, LDL oxidized na homocysteine." Oulu University Library 2003.
Vagianos K, Bector S, McConnell J, Bernstein CN. "Nyocha nke nri nke ndị ọrịa na-arịa ọrịa stroel." JPEN J Parenter Enteral Nutr 2007 Jul-Aug; 31: 311-319.