Ihe akaebe na-akwado iji steroid-eguzogide ọgwụ
A. Plasma mgbanwe, nke a na-akpọkwa "plasmapheresis," ka American Academy of Neurology (AAN) na-atụ aro iji mee ka ndị mmadụ laghachi azụ dị nro na nlọghachi-na-enye ọtụtụ sclerosis (RRMS), dịka a na-ewere ya na "enwere ike ịrụ ọrụ."
Otú ọ dị, a na-atụle mgbanwe plasma dịka usoro nhazi nke abụọ maka nlọghachi azụ nke na-adịghị anabataghachi usoro Solu-Medrol - ọ bụghị kama Solu-Medrol.
Enwere nkwado site na AAN maka ọgwụgwọ nlọghachi na RRMS bụ na January 2011 ma bụrụ mgbanwe na nduzi 1996, ebe a na-akpọ usoro ahụ dịka "nkwa" na "ikekwe ọ bara uru."
Ekwesiri iburu n'obi na mgbanwe nke plasma NKE AAN adighi akwado ya ka o mee ihe n 'onu ogugu nke ozo di elu ma obu mbu nke otutu ogwu.
Gịnị mere Exchange Exchange ga-eji rụọ ọrụ?
Mgbanwe nke Plasma na-ewepu ihe na-emerụ ahụ na-ekesa n'ime mmiri (plasma) ọbara. N'ihe gbasara MS, nke a bụ ọgwụ nje megide protein nke na-emepụta ihe dị na ya , yana mkpụrụ ndụ T na ikekwe mkpụrụ ndụ ndị ọzọ na-adịghị ahụkebe bụ ndị nwere ike idozi ihe omimi.
A na-eche na iwepu mkpụrụ ndụ ndị a n'oge nlọghachi nwere ike ịkwụsị oge nlọghachi na mmebi nke mbufụt. Otú ọ dị, ozugbo a na-agbachi ọrịa ndị a ma ọ bụ debe ha n'ime ọnya ahụ , mgbanwe nsị plasma agaghịzi ewepu ha ma ọ ga-abụ na o nweghị uru ọgwụgwọ ọ bụla.
Kedu ihe bụ Ngosipụta maka Exchange Plasma maka RRMS Relapses?
Na obere obere ikpegharị crossover, mmadụ iri abụọ na abụọ na RRMS ma ọ bụ ọrịa ndị ọzọ na-emetụta ọbara na-egbuke egbuke (transverse myelitis, neuromyelitis optica) nke na-akpata nnukwu mgbaàmà gụnyere n'ime nnyocha nke mgbanwe plasma. Ndi mmadu nile emeghi ihe obula nke Solu-Medrol na onu ogugu nke EDSS bu 7.5 mgbe ha malitere nyocha.
Mmadụ itoolu nwere "akara" na mmụba "ịdị mma" mgbe mgbanwe mgbanwe plasma gasịrị. Mmadụ ise n'ime ha nọgidere na-enwe mmelite maka ruo afọ 3.
Na obere obere nke ikpe, mmadụ anọ nwere RRMS na-alaghachi azụ nke na-azaghị Solu-Medrol. E nyere onye ọ bụla 5 mgbanwe nke plasma. Otu onye "akara" akara, mmadụ abụọ nwere "mgbake" (ọ bụ ezie na otu onye n'ime ha chọrọ ka e mee ọgwụgwọ nke ugboro 5), otu onye nwere "mgbake" dị nwayọọ.
Ndabere ala
Ọ bụrụ na ị na-enwe nkwarụ siri ike nke na-adịghị anabata Solu-Medrol, dọkịta gị nwere ike ịme atụmatụ mgbanwe nke plasma. Mgbanwe mgbanwe Plasma bụ usoro dị mma nke na-adịghị emerụ ahụ ma ọ dịghị eme ka ahụ ghara ịda mbà.IHE: A na-ejikwa ndị na-enwe ọtụtụ sclerosis bụ ndị a chọpụtara na ha na-arịa ọrịa na-aga n'ihu na Tysabri. A na ejikarị ya na ọgwụ. (Iji mụta ihe ọzọ: Q. Gịnị bụ ọgwụgwọ maka PML?
Maka nchịkọta nke usoro mgbanwe mgbanwe plasma, gụọ: Exchange Plasma (Plasmapheresis) maka MS na Ọrịa Na-ahụ Maka Ọrịa Na-adịghị
Isi mmalite:
Cortese I, Chaudhry V, Ya mere YT, Cantor F, Cornblath DR, Rae-Grant A. Nlereanya nduzi dabeere na nchịkwa: Plasmapheresis na ọrịa na-adịghị mma: Akuko nke Nkà Mmụta Nkà Mmụta Ahụike na Nkà na Ụzụ nke American Academy of Neurology. Nchọpụta ihe. 2011 Jan 18, 76 (3): 294-300.
Habek M, Barun B, Ụdị Z, Brinar VV. Ngwọta nke nlọghachi na-adịghị anabataghachi na steroid na mgbanwe plasma na otutu sclerosis. Ịkpọ oku oku. 2010 Jun; 14 (3): 298-302.
Lehmann HC, Hartung HP, Hetzel GR, Ogwu O, Kieseier BC. Exchange Plasma na Disorders Neuroimmunological, Nkebi nke 1: Ọgwụgwọ na Ngwọta nke ọrịa inflammatory Central Nervous System Disorders. Arch Neurol. 2006; 63: 930-935.
Weinshenker BG, O'Brien PC, Petterson TM, et al. Ọnwụnwa a na-etinyeghị aka nke mgbanwe plasma na nnukwu usoro nhụjuanya nke etiti na-eme ka ọrịa na-egbu egbu. Ann Neurol. 1999; 46: 878-886.