Ihe Ị Kwesịrị Ịma Banyere Iwere Metformin Ọ bụrụ na ịnwe PCOS
Ọ bụrụ na ị nwere Ọrịa Polycystic Ovary ( PCOS ) ma bụrụ nke a gwara metformin, o nwere ike inwe ọtụtụ ajụjụ na nchegbu maka ịṅụ ọgwụ a. Ọnụ ọgụgụ ka ukwuu nke ndị inyom nwere PCOS nwere nnukwu insulin na-eme ka ịba uru dị ukwuu, ọchịchọ, na ọbụla ọchichiri na akpụkpọ gị. Ka oge na-aga, ikuku dị elu nke insulin nwere ike ime ka ị na- eguzogide insulin ma ọ bụ ghọọ ụdị ọrịa shuga 2.
Metformin na - arụ ọrụ iji belata insulin gị na belata ihe ize ndụ gị maka ọrịa shuga.
Isiokwu a ga - egosi gị ihe ịkwesịrị ịma banyere ịmalite metformin ma ọ bụrụ na ị nwere PCOS.
Kedu ka ọrụ Metformin si eme?
Metformin bụ otu n'ime ọgwụ ndị kasị ochie na nke kachasị amụba na United States. Aha ndị ọzọ maka metformin gụnyere Glucophage, Glucophage XR, glumetza, na fortamet. Ọ bụ ezie na anaghị akpọ ya maka ndị inyom nwere PCOS, metformin bụ otu n'ime ọgwụ ndị kachasị eji ejikwa ọnọdụ ahụ. Metformin amụọla ụmụ agbọghọ dịka nwata dị afọ 8, ụfọdụ ndị na-eme nnyocha na-atụ aro ya iji gbochie mmalite nke PCOS. Metformin na-arụ ọrụ dị ka insulin-sensitizer iji belata mmepụta nke glucose gị. Metformin na-ebelata ọbara glucose na insulin n'ọtụtụ ụzọ atọ:
1. Ọ na-egbochi imeju nke glucose.
2. Ọ na - eme ka ọnyá gị, ahụ ike gị, abụba ya, na mkpụrụ ndụ gị na - emepụta insulin ahụ gị.
3. Ọ na-ebelata absorption nke carbohydrates ị na-eri.
Ọnụ ọgụgụ nke metformin maka ụmụ nwanyị nwere PCOS bụ 1,500 mg na 2,000 mg kwa ụbọchị.
Uru nke Metformin
E wezụga ịdọrọ ọkwa glucose na insulin, metformin nwere ike inye ụmụ nwanyị nwere PCOS uru ahụike ọzọ. Metformin nwere ike ime ka ọkpụkpụ na-achịkwa ma gbanwee usoro mgbatị nke menstual.
Nke a pụtara na ọ bụrụ na ị na-arụsi ọrụ ike, ị ga-eji akara nwa iji gbochie ịtụrụ ime, ọbụlagodi ma ọ bụrụ na ịnweghị oge gị. Metformin nwere ike ọbụna ịme ka cholesterol na mgbaàmà hirsutism dị ka ọnya na ịba ụba ntutu. Metformin nwere ike inye aka ma ọ bụrụ na ị na- eri nri na ahụike na-edozi ahụ, ma ọ bụghị ọgwụ ọjọọ na-efu. Iwere metformin mgbe ime ime nwere ike belata ihe ize ndụ nke ọrịa shuga gestational na ekwesịrị ka ekwurịta ya na dọkịta gị.
Kedu maka mmetụta dị n'akụkụ?
N'ozuzu, ọtụtụ ndị mmadụ nwere ike ịnagide metformin dị mma. Ihe mmetụta kachasị emetụta ahụ mgbe mbụ ị na-amalite na-ewere ya bụ GI metụtara na nwere ike ịgụnye ọgbụgbọ, gas, bloating, abdominal discomfort and diarrhea. Ụfọdụ ndị na-achọpụta na nsụgharị-azụ nke metformin bụ nke dị nro na usoro nsị nke ọma na ka mma.
Metformin kwesịrị iri nri iji belata mmetụta ndị ọzọ. A na-atụ aro nwayọ nke metformin karịrị izu ole na ole maka nsonaazụ kacha mma. Iri ihe oriri na ihe oriri nwere ike ime ka nsogbu metformin na-eme ka njọ. Ị nwere ike ịchọpụta na ị na-arụ ọrụ na onye na- edozi nri na-edozi ahụ bụ ọkachamara na PCOS na-enye aka ịmepụta atụmatụ nri nke kachasị mma maka mkpa pụrụ iche gị.
Metformin nwere ike imetụta absorption nke vitamin B12 . Iji ogologo oge na akwa doses nke metformin na-eme ka ohere nke vitamin B12 dịkwuo oke. Enweghị vitamin B12 nwere ike ime ka mgbanwe ọnọdụ uche, mgbakasị ncheta ma nwee ike imebi ụbụrụ na usoro ụjọ. I kwesiri igbakwunye nri gị na vitamin B12 ma mee ka ọkwa gị kwa afọ. Ntọala kacha mma nke vitamin B12 kwesịrị> 450 pg / mL. Mmiri dị elu homocysteine na urinary methylmalonic acid (MMA), ọkwa nke edozi na B12, na-egosikwa ụda B12.
Lactic acidosis bụ mmetụta dị nta nke metformin.
A naghị atụ aro ịṅụ mmanya mgbe ị na metformin.
Enwere ihe ndi ozo di na Metformin?
Enweghị ihe mgbakwunye maka metformin kama maka ndị ahụ na-enweghị ike ịnagide ya ma ọ bụ na ị chọghị ịṅụ ọgwụ a chọrọ, enwere ụzọ ndị ọzọ iji meziwanye insulin ma ọ bụrụ na ị nwere PCOS-na-enweghị mmetụta ndị ọzọ. Ihe kachasị mkpa bụ ịgbaso nri dị mma ma na-arụ ọrụ ahụ mgbe niile. N-acetyl cysteine bụ antioxidant nke e gosipụtara na otu ikpe a na-achịkwa na-arụ ọrụ na-arụ ọrụ yana metformin maka mbenata insulin na cholesterol na ụmụ nwanyị nwere PCOS. A chọtara myo-inositol iji weghachite ntughari nke na-emepụta afọ ime karịa metformin. E gosipụtara Myo-inositol iji melite insulin na akụkụ ndị ọzọ metabolic nke PCOS.
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