Ụfọdụ ndị na-eme ihe ngosi Proton Pụrụ Na-enweta Onyonyo
Ndị ọgwụ na-edekarị ọgwụ maka ọgwụgwọ Gastroesophageal Reflux Disease (GERD) bụ prohibit pump inhibitors (PPI).
Ndị na-emepụta ihe ndị na-emepụta proton bụ ndị na-ebelata acid. Ndị dọkịta na-agwa ndị ọzọ ka ha na-emeso ndị mmadụ ọtụtụ ọnọdụ tinyere:
- Ọrịa obi (ọrịa ọrịa reflux gastroesophageal)
- Ọrịa nke afọ ma ọ bụ eriri afọ
- Ọgwụgwọ maka Helicobacter pylori
- Mkpụrụ nke afo acid ( Zollinger-Ellison Syndrome )
Kedu otu a si arụ Ọrụ
Otu n'ime ihe mere ndị na-agbachi mgbapụta na-eji eme ihe na-abụkarị n'ihi na ha na-enwekarị ihe ịga nke ọma ịkwụsị nkuja.
Afọ gị na-emepụta acid iji nyere aka belata nri ka ọ dị mfe nsị. N'ọnọdụ ụfọdụ, acid a nwere ike ime ka ọnyá na duodenum gị pụta (aha ahụike maka akụkụ elu nke obere eriri afọ gị) na-akpata nrịkota obi na ọbụna ọnya afọ.
Afọ a nwere mgbapụta, nke a na - akpọ mgbapụta mmiri nke gastric, nke na - emepụta afo stomach. Ndị na-ebute ihe ndị na-emepụta acid na-egbochi ikuku nke acid n'ime afo site n'igbu ha. Mbelata nke afo acid nwere ike inyere ọnya aru aka na reflux ka osiri.
E Nwere ọgwụ ndị nwere ọgwụ
Nke a bụ ihe dị asaa nke dịnụ, ụfọdụ ndị na-ederede na ụfọdụ site na ndenye ọgwụ:
- Aciphex (Rabeprazole)
- Nexium (Esomeprazole)
- Prevacid (Lansoprazole) -nweghi n'elu-na-counter
- Prilosec (Omeprazole) - enweghi n'elu-na-counter
- Protonix (Pantoprazole)
- Dexilant (Dexlansoprazole)
- Zegrid (omeprazole / sodium bicarbonate) - enweghi n'elu-na-counter
Ihe Nlekọta Na-emeso GERD
Ọ bụrụ na dọkịta gị na-atụ aro ka ị ṅụọ GERD, o yikarịrị ka ọ na-atụ aro ka ị gbanwee ụdị ndụ gị dịka ibu arọ (ọ bụrụ na ibu oke ma ọ bụ ibu), na-ebuli isi nke ihe ndina gị n'abalị, ma ghara iri nri ruo awa abụọ ma ọ bụ atọ tupu ị lakpuo ụra.
A na-ewerekarị PPI otu ugboro n'ụbọchị 30 ruo 60 tupu oge ụtụtụ, ma were ya maka izu asatọ, mgbe ahụ ka dọkịta gị ga-atụleghachi mmetụta ị na-enwe. Ọ bụrụ na ị dị mma, dọkịta gị nwere ike ibelata ọgwụ gị ma ọ bụ ọbụna kwụsị ọgwụ gị. N'iji nlezianya meeghachi omume, dọkịta gị nwere ike ịba ụba gị ugboro abụọ n'ụbọchị. Ọ bụrụ na ị ka na-enweta enyemaka maka GERD gị, dọkịta gị ga-eleba anya na-akpọga gị na ọkachamara (onye gastroenterologist) ma ọ bụ nyochaa nyocha ahụ.
Achọghị ọgwụgwọ PPI iji were ogologo oge, n'ihi ya, ihe mgbaru ọsọ bụ iwepụta ya n'oge kachasị dị ala maka oge kachasị dị mkpirikpi nke nwere ike ime ka obi nkoropụ gị kwụsị ma gbochie nsogbu dịka ọrịa ọnya. Nke a bụ ihe mere ịgbasochi anya na dọkịta gị ji dị mkpa - ya mere a pụrụ ịhazi atụmatụ nlezianya anya ma gbanwee dịka ọ dị mkpa.
Ihe I Kwesịrị Ịmara Tupu IKE NDỊ
N'afọ 2012, FDA nyere ịdọ aka ná ntị ndị na-azụ ahịa na-eji PPI nwere ike jikọta ya na ohere nke ọrịa na-arịwanye elu, dị ka na oyi baa, nakwa dị ka afọ ọsịsa metụtara Clostridium siri ike. Ọrịa na nje ahụ Clostridium siri ike na- eme ka e nwee mmiri mmiri, ihe mgbu abdominal, na ahụ ọkụ.
Tụkwasị na nke a, ejikọtawo ihe ndị a na nchịkọta calcium dị ntakịrị na ihe ize ndụ nke ọkpụkpụ ọkpụkpụ (na ndị na-ewere nnukwu doses nke PPI-pụtara ihe karịrị otu ugboro n'ụbọchị na otu afọ ma ọ bụ karịa).
A na-ejikọta ya na belata magnesium absorption na gut, ya mere onye dọkịta gị nwere ike ịlele oge magnesium gị oge.
Okwu Site
Ọ dị ezigbo mkpa iji ọgwụ ọ bụla, gụnyere proton pump inhibitors, n'okpuru nduzi nke dọkịta, ọ bụrụgodị na ọ dị n'elu-na-counter. Nke a bụ iji hụ na a na-ewepụ onye na-emepụta proton mgbapụta n'ụzọ ziri ezi na maka ezi ihe kpatara ya - nchọpụta kwesịrị ekwesị bụ isi, n'ihi na e nwere ọtụtụ nsogbu ahụike nke nwere ike ịkọ GERD.
Isi mmalite:
> American College of Gastroenterology. (June 2008). Nsogbu GI Na-ahụkarị Mpịakọta nke 1: Ịghọta ụfọdụ n'ime ọgwụ ndị a na-edekarị maka GERD & Ulcers.
> Johnson, T. (June 2014). Nchịkọta nri na ọgwụ ọjọọ nke United States: Njiye ihe nkwụnye ihe mgbapụta na ihe ize ndụ nke ndị gbawara agbawa na ndị okenye.
> Katz, PO, Gerson, LB, Vela MF Ntuziaka maka nyocha na njikwa nke ọrịa reflux gastroesophageal. Am J Gastroenterol. 2013 Mar; 108 (3): 308-28.
> Lanza, FL, Chan, FK, Quigley, EM, Mee Kọmitii Kọmitii nke American College of Gastroenterology. Ntuziaka maka igbochi nsogbu ọrịa ọnya NSAID. Am J Gastroenterol. 2009 Mar; 104 (3): 728-38.
> Nchịkwa nri na ọgwụ ọjọọ na US. (February 2012). Nkwurịta okwu nchebe nke FDA: Clostridium siri ike - nwere afọ ọsịsa nwere ike jikọta ya na mmiri ọgwụ ọjọọ a maara dịka prohibit pump inhibitors (PPI).