Glucosamine / Chondroitin Arthritis Intervention Trial Results

Ihe Nchoputa US na European Trial Ekepụtara maka Glucosamine

Na Ụlọ Akwụkwọ American Academy of Rheumatology Annual Scientific Meeting (2005), e si na nyocha abụọ glucosamine pụta. Ihe ndi nchoputa, ndi dibia, na ndi nriaria bu ndi choro ikwenye na glucosamine bu ihe puru ime ihe ozo maka arthritis .

GAIT (Glucosamine / Chondroitin Arthritis Intervention Trial) Oge I

Na GAIT (Glucosamine / Chondroitin Arthritis Intervention Trial), ihe fọrọ nke nta ka ọ bụrụ ndị ọrịa 1,600 nwere ọrịa ogbu na nkwonkwo na-egbu mgbu bụ ndị e si na 16 ụlọ akwụkwọ mmụmụ nke United States maka ọmụmụ ihe ahụ. Ndị na-amụ ihe ahụ enweela nnukwu ihe mgbochi ikpere ma nwee ihe ngosi x-ray nke osteoarthritia ikpere. N'oge ọmụmụ GAIT, ndị ọrịa:

Ihe si na GAIT (Glucosamine / Chondroitin Arthritis Intervention Trial)

Ntuziaka (Glucosamine Unum na Ọrịa Mgbu)

E nwere mmadụ 318 nọ na ọmụmụ GUIDE na ikpere osteoarthritis (88% inyom). A na-eme ka ndị ọrịa ghara ikwe ka glucosamine sulfate soluble ntụ ntụ (1500 mg otu ugboro n'ụbọchị), acetaminophen (1000 mg ugboro atọ n'ụbọchị), ma ọ bụ placebo karịrị ọnwa isii. A na-ekwe ka ìgwè niile kwere ibuprofen dị ka dị mkpa.

Nsonaazụ sitere na GUIDE (Glucosamine Unum In Diseffice)

Oge nke II na oge nke III GAIT Results

E bipụtara nsonaazụ sitere na usoro nke abụọ nke ọmụmụ GAIT n'akwụkwọ akụkọ Arthritis & Rheumatism na 2008. Phase II nyochare nchịkọta nke glucosamine na chondroitin maka igbochi mmebi nkwonkwo ikpere. Nchikota glucosamine na chondroitin enwegh i ihe bara uru n'igbochi mmekorita ndi ozo na osteoarthritis karia placebo.

Ndị na-amụrụ ihe ndị na-atụghị anya na ha nwere ohere karịrị oge abụọ nọ n'etiti ìgwè ndị were glucosamine ma ọ bụ chondroitin naanị. Eleghị anya, iweghachị abụọ ahụ na-emetụta absorption, nke nwere ike ịkọwa njirimara nke ntinye mgbe ejiri ya mee ihe.

Oge nke III, bụ nke a tụlere ngụkọta nke afọ anọ nke data, gosiri na ihe mgbakwunye na njikọta ma ọ bụ naanị enweghi uru dị ukwuu maka mgbu mgbu nke ikpere karịa celecoxib ma ọ bụ placebo. E bipụtara ihe ndị a na 2010 n'akwụkwọ akụkọ Annals of Rheumatic Disease .

Nkwenye maka Glucosamine

Ndabere ala

N'afọ 2012, Ụlọ Ọrụ American Academy of Rheumatology bipụtara ọgwụgwọ ọgwụgwọ maka ọrịa ogbu na nkwonkwo. Na nduzi, chondroitin ma ọ bụ glucosamine adịghị atụ aro maka ọgwụgwọ mbụ nke ọrịa ogbu na nkwonkwo. Nhọrọ nke chondroitin na glucosamine nanị ma ọ bụ na nchikota nwere ike ọ gaghị abụ ọgwụgwọ dị irè maka ndị ọrịa niile. Ọ nwere ike ịrụ ọrụ maka ụfọdụ ndị ọrịa, ma ọ bụrụ na ọ na-arụ ọrụ maka gị, nọgide na - agwọta ya.

Isi mmalite:

Mmetụta nke glucosamine na / ma ọ bụ cholestroitin sulfate na-arịwanye elu nke ikpere osteoarthritis: akụkọ sitere na glucosamine / chondroitin arthritis na-anwale ikpe. Sawitzke et al. Arthritis & Rheumatism. 2008 Ọkt; 58 (10): 3183-91.
http://www.ncbi.nlm.nih.gov/pubmed/18821708

Glucosamine / Chondroitin Arthritis Intervention Trial (GAIT). NIH. Gbanwee na Jenụwarị 2012.
https://nccih.nih.gov/research/results/gait

Nrụpụta ahụ na nchekwa nke glucosamine, chondroitin sulphate, nchikota ha, celecoxib ma ọ bụ placebo ka a na-agwọ ọrịa ogbugbu nke ikpere: afọ 2 sitere na GAIT. June 2010. Ọkọlọtọ nke Ọrịa Rheumatic. 2010; 69: 1459-1464
Akwukwo Igbo:

Ntuziaka maka iji ọgwụ ndị na-adịghị agwọ ọrịa na ọgwụ na-agwọ ọrịa na Osteoarthritis nke Aka, Hip, na Knee.American College of Rheumatology 2012. (Ọgwụgwọ Arthritis Care & Research Vol. 64, No. 4, April 2012, pp 465-474.)