Kedu ihe bụ SAM-e (S-adenosylmethionine)?

SAM-e May Nweta Osteoarthritis na Mwute

Mpị na ịdọ aka ná ntị na-ezokarị gburugburu ihe oriri. SAM-e (S-adenosylmethionine) so n'ime ihe oriri ndị na-eri nri nke na-ekwu na ha nwere mmetụta bara uru maka ịgwọ ọrịa ogbu na nkwonkwo .

Kedu ihe bụ SAM-e?

SAM-e (S-adenosylmethionine) abughi ọgwụ ogwu , kama o bu onyinye nke anu aru anyi sitere na methionine, amino acid nke achutara na nri ndi nwere protein.

Dị ka ihe mgbakwunye, a na-eme Sam-e site na tefist fermented ma ọ bụ mechie ya.

Kedu ka SAM-e si arụ ọrụ?

Site n'enyemaka ndị ọzọ site na vitamin B-12 na folic acid, SAM-e na-ahapụ òtù methyl site na ya mejupụtara anụ ahụ na akụkụ ya. Site na nke a, SAM-e na-enyere aka na mmezi nke membranes cell, iwepụ ihe ndị na-egbu egbu site na ahụ, na mmepụta nke ndị na-eme ka ndị na-ahụ maka ọnọdụ uche.

N'ikpeazụ, SAM-e yiri ka ọ na-edozi ihe karịrị 35 usoro dị iche iche. Site na ntiwapụ nke SAM-e, mkpụrụ ndụ ndị ọzọ na-emepụta nke nwere ike inye aka mee ka cartilage ha . A na-eche na SAM-e na-amụba mkpụrụ ndụ ndị na-emepụta cartilage (nke a maara dị ka chondrocytes), na-emetụta ọkpụkpụ cartilage, na ikekwe ọ na-ebelata mmebi nke chondrocytes.

Kedu ka SAM-e si chọta?

E jiriwo SAM-e mee ihe ruo ọtụtụ iri afọ na Europe iji mesoo arthritis na ịda mbà n'obi. A chọpụtara ihe dị n'ime afọ 1950 na National Institutes of Health.

N'afọ ndị 1970, mgbe ụlọ akwụkwọ Ịtali mụtara ịmịpụta ya na omenala ndị mmadụ, a na-enyocha SAM-e dị ka onye na-egbochi nsogbu. Ụfọdụ n'ime ndị ọrịa mbụ e nyere SAM-e maka ịda mbà n'obi na-arịa ọrịa ogbu na nkwonkwo. Ihe na-egbochi ọrịa arthritis nke SAM-e mezuru mgbe ndị a na-arịa ọrịa gosipụtara ahụ efe site na nkwonkwo mgbu ha , tinyere ịda mbà n'obi ha.

Mgbochi ọrịa arthritic na-egosi Sam-e nwere ike inye aka nkwụsị na ncha, yana ihe mgbu. Ọ nwere ike ime ka ọ dịkwuo mma. O nwere ike inyeaka ihe mgbaàmà nke fibromyalgia , bursitis , na tendinitis, na ihe mgbu dị ala, na-enyekwa uru bara uru maka ọrịa ogbu na nkwonkwo.

Gịnị Ka Nnyocha Na-ekpughe?

Ndị ọrịa ọrịa ogbu na nkwonkwo abuanawo na ọmụmụ na-atụnyere SAM-e to placebo ma ọ bụ NSAID ndị ọzọ (ọgwụ ndị na-adịghị egbochi ọgwụ ọjọọ) . Na nchịkọta ihe atụ, nke e bipụtara na Journal of Family Practice, May 2002, ndị ọrịa SAM-e nwetara ezigbo enyemaka dịka ndị ọrịa na-ewere NSAIDs. N'ọnwa ọzọ (BMC Diskasị Ọrịa 2004), nke bụ ikpe ikpe-azụ nke na-atụle ihe dị ka otu narị afọ na iri abụọ na abụọ n'ogologo SAM-e ruo 200 mg Celebrex (celecoxib) maka izu iri na isii, e kwubiri na SAM-e ji nwayọọ nwayọọ mee ihe dị ka Celebrex oge maka ikiri osteoarthritis. Enweghị atụmatụ ọ bụla iji kụziere mmadụ abụọ kpuru ìsì, ebe a na-achịkwa ebe a na United States nke dị mkpa iji chọpụta na ọgwụgwọ bara uru.

Enwere mmetụta ọ bụla metụtara ya na SAM-e?

Ụdị ojiji nke SAM-e maka osteoarthritis bụ 600 ruo 1,200 mg kwa ụbọchị. Enwere ike inwe mmetụta ndị ọzọ, na enwekwu ike maka mmetụta ọjọọ na nrịba dị elu.

Mmetụta ndị nwere ike ịgụnye ọgbụgbọ, flatulence, afọ ọsịsa, na isi ọwụwa.

Ndabere ala

A na-ere SAM-e dịka ntinye n'elu-na-counter na United States. Na Europe, a na-ere ya site na ọgwụ. Nkwupụta ahia na-ekwu na ọ na-akwalite "ahụ ike" na "mmetụta uche". Nchịkwa nri na ọgwụ ọjọọ, nke na-elekọta ahịa ahịa na-eri nri, adịghị ekwe ka nkwupụta ahụike na nkwakọ ngwaahịa nke mgbakwunye.

_{Isi mmalite:}

_{SAM-e. Nchịkọta Ntụkọ Ọrịa Taa. Ntọala Arthritis. Ịbanye na 01/30/2016.
http://www.arthritis.org/living-with-arthritis/treatments/natural/supplements-herbs/guide/sam-e.php}

_{Nchebe na nrụpụta ọrụ nke S-adenosylmethionine (SAM-e) maka ọrịa ogbu na nkwonkwo. Soeken KL et al. Journal of Family Practice. Mee 2002.
http://www.ncbi.nlm.nih.gov/pubmed/12019049}

_{S-Adenosyl methionine (SAM-e) na vescoxib maka ọgwụgwọ ọrịa osteoarthritis: Ọhụụ okpukpu abụọ-n'elu ikpe. Ahụhụ na-arịa ọrịa BMC. Wadie Na Najm et al. February 2004.
http://www.biomedcentral.com/1471-2474/5/6}

_{Cowley, Geoffrey. March 22, 1999. "Sammy Solution." Newsweek 133 (12): 65.}