Ngwakọta Viscosupplement Na-eme Ka Njirimara nke Njikọ Njikọ Ziri Ezi Meghachiri
Synvisc (hyl GF 20) bụ ihe na-agbanwe agbanwe, viscous, mmiri dị arọ nke dị arọ nke na-agụnye mmiri A, mmiri hyel B, na mmiri nnu. Hylan A na hylan B na-enweta site na hyaluronan (nke a na-akpọ sodium hyaluronate) nke sitere na combs. Hyaluronan bụkwa ihe a na-ahụ anya na ahụ, kpọmkwem, na nnukwu nkwonkwo.
Omume hyaluronan nke ahụ na-eme dị ka mmanu mmanu na ihe ọkụkụ nke dị mkpa maka ịrụkọ ọrụ ọnụ.
Synvisc bụ otu n'ime hyaluronates nke a na-eji na ọgwụgwọ a maara dika viscosupplementation . A na-akpọ ọgwụgwọ mgbe ụfọdụ dịka ọgwụgwọ nkwonkwo, hyaluronan injectons, ma ọ bụ injections hyaluronate.
Ntu maka Synvisc
A nabatara ọgwụ mgbochi Synvisc maka ọgwụgwọ nke ihe mgbu ndị ọrịa na-arịa ọrịa osteoarthritis nke ikpere ndị na-enweghị ike ịzaghachi usoro ọgwụgwọ ndị ọzọ, dịka ọgwụ analgesics ma ọ bụ ọgwụ ndị na-abụghị ọgwụgwọ. N'ọrịa ogbu na nkwonkwo, enwere ike inwe oke hyaluronan ma ọ bụ ịdị hyaluronan nwere ike ibelata. Enwere Synvisc maka nkwonkwo ndị ọzọ na-enyocha, ma ọ kabeghịrịrị anakwere.
A na-agbara Synvisc aka, jiri sirinji nwere 2 ml, ozugbo n'ime nkwonkwo ikpere iji weghachite ngwongwo na lubricating properties of flu joint joint.
Enwere ihe Synvisc ọzọ, nke a maara dịka Synvisc-One, nke a na-edozi dịka otu (oge) oge na-ejiri intra-articular (6 ml).
Synvisc Injections - Azụ
- A na-amụrụ ngọngọ maka ọgwụgwọ ọrịa ogbu na nkwonkwo kemgbe afọ ndị 1970.
- Synvisc bụ FDA kwadoro na 08/08/97.
- A na-enyekarị mmịpụ Synvisc dị ka usoro nke 3 injections, otu ugboro n'izu, otu izu zuru ezu. Synvisc-Ekepụtara otu dịka otu ogwu, dị ka ihe ọzọ na usoro nke atọ na Synvisc.
- Iji nweta nsonaazụ kachasị mma, a na-ewepụta mmiri synovial osteoarthritic dị na ikpere tupu akpa ọgwụ.
- A na-ewere Synvisc ọgwụgwọ ma ọ bụ ọgwụgwọ, ọ bụghị ọgwụ.
Mmetụta na Mmetụta Na-akpata
Ihe mmetụta kachasị emetụta ndị Synvisc injections gụnyere ihe ngbu na ikpere injected, ọzịza na ikpere injected, na nkwonkwo njikọ . Ihe ndị ọzọ nwere ike ịdaba na mkparịta ụka na-agụnye arthralgia (ihe ngbu na nkwonkwo), nkwonkwo nkwonkwo , nkwonkwo njikọ, nkwonkwo njikọ, nkwonkwo aka , ihe mgbu na ebe ogbugba, arthritis, arthropathy, na adịghị mma.
Nlekọta mgbasa ozi nke usoro usoro nke atọ nke Synvisc kpughere mmetụta ndị ọzọ na-adịghị adịte aka gụnyere nsị, ọkụ, ọkụ, ọgbụgbọ, isi ọwụwa, dizziness, ụfụ, nhịahụ muscle, malaise , nsogbu respiratory, edema ederede, na adịkarịghị, thrombocytopenia (obere platelets ).
Nkwekọrịta na ịdọ aka ná ntị
E kwesịghị ịdịnye Synvisc n'ime ndị ọrịa na-ahụ maka hypersensitivity mara na ngwaahịa hyaluronan. Ọzọkwa, a gaghị etinye Synvisc ikpere ụkwụ na nkwonkwo nkwonkwo, ọrịa anụ ahụ ma ọ bụ ọrịa, ma ọ bụ ọrịa na mpaghara gbara gburugburu ebe ahụ ịgbawa.
Ọ bụ naanị Synvisc ka a ga - eji mee ihe dịka nkedo intra-articular (n'ime nkwonkwo).
Ọ bụrụ na a na-agbanye ya n'èzí na nkwonkwo ya na anụ ahụ synovial ma ọ bụ ụbụrụ njikọta, ihe omume ọjọọ ma ọ bụ nke usoro ihe omume nwere ike ime. Mkpịsị aka nke Synvisc (n'ime arịa ọbara) nwere ike ịkpata ihe ọjọọ na-eme ma ọ bụrụ na a ghaghị izere ya.
Mgbe a na-ejikọta Synvisc, a na-atụ aro na ndị ọrịa kwesịrị izere ihe siri ike ma ọ bụ ọrụ ogologo oge ruo 48. Soro dọkịta gị kwurịta okwu gbasara ụfọdụ gbasara gị.
Nchebe na irè Synvisc n'ime ụmụ nwanyị dị ime ma ọ bụ ụmụ nwanyị nọọsụ adịghị eguzobe.
Ọ bụrụ na ị nwere allergies na feathers, àkwá, anụ ọkụkọ, ma ọ bụ ngwaahịa ndị ọzọ sitere na nnụnụ - gwa dọkịta gị.
Iji Synvisc tụnyere Corticosteroid Injections
Synvisc nwere ike iji ya tụnyere ọkpụkpụ corticosteroid nke nwere ike ịmalite ngwa ngwa karịa obere oge nke ọrụ karịa Synvisc. A na-eleghachi anya injections nke Synvisc dịka nchekwa karịa corticosteroids na ndị ọrịa nwere njakịrị nke nwere ike ime ka corticosteroids contraindicated. Ọzọkwa, ekwesiri iburu n'uche na iji NSAID nwere ike belata na ụfọdụ ndị ọrịa na-eso Synvisc injections.
Isi mmalite:
Ozi Ndidi Synvisc, Sanofi US.
http://products.sanofi.us/synvisc/synvisc.html
Ozi Ndidi Synvisc-Otu. Sanofi US.
http://products.sanofi.us/synviscone/synviscone.html
Hylan GF 20: Nyochaa Nchedo na Mgbalị Ọgwụ na Nchịkwa nke Nsogbu Na-ahụ Maka Osteoarthritis. Magliore A. et al. Nyocha Ahụike Clinical: Ọrịa Ogbu na nkwonkwo. 2010; 3: 55-68.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998981/