Berberine bụ chemical dị n'ọtụtụ ụdị herbs, dịka ogbugbo, mgbọrọgwụ, rhizomes nke osisi ndị a hụrụ n'ụwa dum, yana mgbakwunye na ụlọ ahịa ihe oriri. Enwere ọtụtụ uru bara uru nke berberine kemgbe ọtụtụ narị afọ, e jiriwo ya agwọ ọrịa dị iche iche na ọgwụ ndị India na Chinese, site na ọrịa shuga na ọrịa.
N'ihi odo odo ya, omenala ụfọdụ na-eji akwa ákwà.
N'ime afọ ndị na-adịbeghị anya, a chọpụtakwara berberine site na ụfọdụ osisi na ịgwọ ọrịa ahụ, ọrịa cancer, ọrịa ogbu na nkwonkwo na obi obi. E nwere ọbụna ụfọdụ ihe àmà na-egosi na berberine nwere ike ịdị irè iji belata cholesterol na triglyceride ọkwa.
Nnyocha ndị dị n'oge a gosiri nkwa
Ọ bụ ezie na e nwere ọmụmụ mmadụ mmadụ ole na ole na-enyocha mmetụta nke berberine na mkpụrụedemede egbugbere ọnụ , ihe ka ọtụtụ n'ime ọmụmụ ndị a na-eduzi na ụmụ anụ na ụmụ oke. A na-achịkọta berberine na ọmụmụ ndị a site n'ọtụtụ mkpuru akwụkwọ, tinyere mgbọrọgwụ ọlaedo na Huanglian.
Na ọmụmụ anụmanụ, a na-elekọta berberine n'ebe ọ bụla n'agbata 100 na 250 mg / kg nke arọ ahụ kwa ụbọchị. Berberine gosipụtara na ọkwa ogo cholesterol dị ala ruo pasent 31. Tụkwasị na nke ahụ, ọ bụ ihe dị ka 32% na ntọala triglyceride ji nwayọọ nwayọọ belata na ọkwa LDL cholesterol ruru 25%.
Ọ bụ ezie na a nwalere HDL , berberine apụtaghị na emetụta ya.
Ihe omuma mmadu ole na ole nke na-enyocha berberine biara ka o kwugharia ihe omumu nke umu anu. A na-enye Berberine 500 mg ndị mmadụ nwere nnukwu cholesterol dị elu abụọ na okpukpu atọ kwa ụbọchị ruo ọnwa atọ. N'ihi ya, ọnụ ọgụgụ cholesterol zuru ezu belata ruo 29%.
Ọnụ ọgụgụ cholesterol na-akpata Triglyceride na LDL na-ebelatakwa n'ihi ihe oriri berberine. Dịka ọmụmaatụ, a na-ewedata ọkwa cholesterol LDL site na pasent 21%, ebe a na-ebelata triglyceride site n'ebe ọ bụla n'etiti 22 na 35%. N'aka nke ọzọ, HDL ọkwa adịghị agbanwe agbanwe na mgbakwunye berberine.
Kedu ka Berberine Lower Cholesterol si eme?
Ọ bụ ezie na ụzọ nke berberine na-arụ ọrụ n'ịkụba cholesterol abụghị nke a maara nke ọma, ndị ọkà mmụta sayensị nwere echiche abụọ dị na nke a dabere na nnyocha ndị na-adịbeghị anya. A na-eche na berberine nwere ike ịbawanye ọnụ ọgụgụ nke ndị nabatara LDL n'ime imeju, nke nwere ike inye aka mee ka LDL cholesterol kwụsị. Berberine na-egosikwa na ọ na-eme ihe nrịba ama nke gụnyere ịme abụba n'ime ahụ. A gosiputala Berberine ime ihe yiri nke ahụ site na igbochi absorption nke lipids si obere eriri afọ.
Ị Kwesịrị Were Berberine na Lower Cholesterol?
Nnyocha ndị na-enyocha iji berberine mee ka cholesterol dị ala na-apụta nkwa, ma, ọ dị mkpa ka a chọkwuo nchọpụta tupu enwere ike ịsonye ya dị ka onye na-eme ka cholesterol-atụlata.
A gaghị enye Berberine nye ụmụ amụrụ ọhụrụ, ebe ọ nwere ike imebi ụbụrụ, ma ọ bụ ụmụ nwanyị dị ime na ndị inyom na-enye nwa ara (ọ nwere ike imebi nwa ebu n'afọ ma ọ bụ nwa ọhụrụ).
Berberine site n'onwe ya siri ike ịchọta dịka mgbakwunye iji mee ka ọkpụkpụ gị belata. Otú ọ dị, ọtụtụ ihe mgbakwunye na osisi na-abụ nke azụmahịa nke nwere berberine dị elu, gụnyere:
- Mgbọrọgwụ Goldenseal ( Hydrastis canadensis L )
- Osisi irighiri oka ohia ( Berberis aquifolium )
- Barberry ( Berberis vulgaris )
- Huanglian ( Coptis chiensis )
Ihe di na berberine di iche n'etiti osisi ohia. Dị ka ọmụmaatụ, goldenseal nwere ike ịnwe ihe ọ bụla n'etiti 1% na 6% nke berberine. Ya mere, ị ga-achọ ịlele akara akwụkwọ mmeju iji mara ọnya berberine, kama ọnụ ọgụgụ nke mkpurugwu, na mbadamba ọ bụla.
Iji hụ mmetụta dị na cholesterol dị na ọmụmụ mmadụ, ọ ga-adị mkpa ka i rie 500 grab berberine ugboro abụọ na ugboro atọ n'ụbọchị.
Ọ bụ ezie na ịnweta ngwa ngwa, ị ga - ahụ maka onye na - ahụ maka ahụike gị tupu ị gbakwunye berberine - ma ọ bụ ihe mgbakwunye ọgwụ ọ bụla nke nwere chemical a - na usoro gị na - egbu egbu. Mmetụta dị iche iche a na-akọ na ngwaahịa ndị nwere berberine gụnyere isi ọwụwa, mkpịsị ọbara ọbara, na ọgbụgbọ. A naghị amachapụta mmetụta nke ọgwụ ndị a na ọnọdụ ahụike ụfọdụ, ọ dịghị ama ma ma ọ bụ berberine nwere ihe mgbakwunye nwere ike iji ọgwụ ọ bụla ị na-ewere.
Isi mmalite:
Abidi P, Chen W, Kraemer FB, Liu J. Ngwurugwu ọgwụ na-edozi ọgwụ bụ LDL-lowering agent with multiple bioactive components and new action mechanisms. J Lipid Res 2006; 47: 2134-2147.
Cicero AFG, Erkek S. Berberine: mmetụ ahụ na mmetụ obi na-egosi na a na-enwe nsogbu. Nutr Diet Supp 2009; 1: 1-10
Ụkpụrụ Nchịkwa. (2015). Berberine [Monograph].
Pirillo A, Catapano AL. Berberine, alkaloid osisi na egbugbere ọnụ na glucose-ịdakwasị ihe onwunwe: si na vitro na-egosi na ọmụmụ ihe. Atherosclerosis 2015; 243: 449-461.