Lumbrokinase bụ enzyme nke sitere na Lumbricus rubellus, ụdị anụ ọhịa. A na-ere ya n'ụdị ntinye nri, a na-ekewa ya dịka enzyme fibrinolytic (ihe na-akwalite mgbawa nke fibrinogen, protein gụnyere mmepụta ọbara). A na-eche na itinye lumbrokinase na-enyekwu ọtụtụ uru ahụike, gụnyere ịkwalite ahụike obi na inyere aka na mgbochi ọrịa strok site n'ịlụso mgbochi ọbara.
Na-eji
Ndị na-akwado echiche na-egosi na lumbrokinase nwere ike inye aka na ọnọdụ ahụike ndị na-esonụ:
Uru
Ka ọ dị ugbu a, nchọpụta banyere mmetụta ahụike nke lumbrokinase dị oke. N'agbanyeghị nke ahụ, e nwere ụfọdụ ihe àmà na ọ na-egosi nkwa maka ọgwụgwọ ụfọdụ ọnọdụ. Nke a bụ ile anya ọtụtụ nchọpụta na uru ndị nwere ike:
1) Obi Obi
Lumbrokinase nwere ike inyere aka na ọgwụgwọ nke angina, dị ka nnyocha mbụ e bipụtara na Journal of Alternative na Complementary Medicine na 2009. Maka nchọpụta ahụ, ndị nchọpụta nyere 10 ndị nwere ọrịa obi na angina ruo otu ọnwa nke ọgwụgwọ na lumbrokinase (na mgbakwunye na nlekọta ha). Site na njedebe ọmụmụ ihe, ọrịa angina mmawo n'ime isii n'ime ndị ọrịa 10 ahụ.
Tụkwasị na nke ahụ, nchọpụta mbụ nke e bipụtara n'akwụkwọ akụkọ China bụ Acta Pharmaceutica Sinica n'afọ 2006 hụrụ na lumbrokinase nwere ike ichebe obi ike.
N'ime ule na oke, ndị na-amụ akwụkwọ kpebiri na lumbrokinase nwere ike chebe megide ischemia myocardial (ọnọdụ a na-ahụ site na nchikota nke akwara na-eme ka ọbara na-erugharị n'obi).
2) Igbu
Nchọpụta mbụ ị na-eme na-egosi na lumbrokinase nwere ike inye aka gbochie ọrịa strok. N'ime nnyocha ọmụmụ 2013 nke a na-ebipụta na akwụkwọ ahụike na Chinese Medical , dịka ọmụmaatụ, mmadụ 310 ndị ụlọ ọgwụ na-agwọ ọrịa strok (ụdị ọrịa strok nke na-eme mgbe a na-egbochi ụbụrụ n'ime ụbụrụ) na ọgwụgwọ ọrịa strok ma ọ bụ ọgwụgwọ kwesịrị ekwesị na capsules lumbrokinase maka otu afọ.
Site na njedebe nke ọmụmụ ahụ, ìgwè na-enweta ọgwụgwọ lumbrokinase nwere ọrịa strok.
N'ime nnyocha 2008 site na European Journal of Pharmacology , ule na mkpụrụ ndụ mmadụ kpebiri na lumbrokinase nwere ike inye aka gbochie nchebe cerebral. (Ọdịdị nke ọbara na-ezughị ezu na ụbụrụ, ụbụrụ cerebral nwere ike ibelata ikuku oxygen na ụbụrụ, ma, n'aka nke ya, na-eduga na ọrịa strok.) Nchọpụta ahụ chọpụtara na lumbrokinase nwere ike imeri cerekral ischemia n'akụkụ ụfọdụ site na igbochi nkedo ọbara.
Tụkwasị na nke ahụ, obere nnyocha e bipụtara na Hemorheology Clinical na Microcirculation n'afọ 2000 chọpụtara na lumbrokinase nwere ike ịba uru n'ịgwọ ụbụrụ ụbụrụ (ụdị ọrịa strok mere site na ịmepụta ọbara n'ime ụbụrụ).
Maka ọmụmụ ihe ahụ, mmadụ 31 nwere ụbụrụ ụbụrụ na-arịa ọrịa lumbrokinase, ebe e zigara mmadụ 20 ndị ọzọ na-achịkwa. Nsonaazụ gosiri na lumbrokinase nwere ike inye aka n'ịgwọ ụbụrụ cerebral n'akụkụ ụfọdụ site na ibelata fibrinogen.
3) Ọrịa shuga
Otu ọmụmụ nke ụmụ anụmanụ na-ebipụta na Ọrịa Shuga na Ọrịa Ọrịa na 2013 na-atụ aro na lumbrokinase nwere ike inye aka ibuso ọrịa nephropathy ọrịa (ọnọdụ akụrụ na-akpata akụkụ nke njikwa ọrịa shuga na ọbara mgbali ).
N'ime nnwale metụtara ọrịa oke mamịrị, ndị ọkà mmụta sayensị chọpụtara na ọgwụgwọ na lumbrokinase nyeere aka chebe megide nephropathy na-arịa ọrịa shuga (ikekwe na-emetụta ụfọdụ enzymes chere na ha ga-arụ ọrụ mmebi akụrụ na ọnọdụ a).
Ihe Ndi Nwere Ike Ime
Ebe ọ bụ na ọmụmụ ihe ole na ole anwalela mmetụta nke lumbrokinase n'ime ụmụ mmadụ, ọ na-adịghị anya ịkọ ma lumbrokinase ọ dị mma maka ogologo oge ma ọ bụ mgbe niile. Ụmụ nwanyị na-amụ nwa, ndị nne na-elekọta nwa, na ụmụ ekwesịghị ikpo lumbrokinase.
Enwerekwa nchegbu na lumbrokinase nwere ike ịkpalite ọtụtụ mmetụta, gụnyere ọgbụgbọ, bloating, afọ ọsịsa, ikpo ọkụ akpụkpọ ahụ, na mmeghachi ahụ nkoropụ.
Ebe ọ bụ na a sịrị na lumbrokinase ga-agbaji fibrinogen (nke a chọrọ iji mee ka mkpịsị ọbara), ọ ga-ekwe omume na mgbakwunye ahụ nwere ike igbochi usoro clotting na-ebute ọbara ọgbụgba.
Ndị na-enwe nsogbu ndị metụtara ọrịa na-agba ọbara agaghị ebute lumbrokinase. Ekwesighi iwere ya tupu oria ogwu. E kwesịghị ịṅụ ya na ọgwụ, ihe mgbakwunye nri, ma ọ bụ herbs nke nwere mmetụta ọbara.
O di nkpa iburu n'uche na enweghi ule ajuju maka ihe nchekwa na nri ndi di na nri di iche iche. Ndị a bụ ndụmọdụ ndị ọzọ gbasara iji ihe oriri na-edozi n'enweghị nsogbu.
Ndabere ala
Ọ bụ ezie na nchọpụta mmalite bụ ihe na-akpali mmasị, enweghi ule ọtụtụ nsogbu-ụdị ụdị ịchọrọ ịchọta itinye ngwaahịa zuru ezu na ọgwụgwọ-na-akwado ihe ndị a. Ọ bụrụ na ị ka na-atụle iji ya mee ihe, ọ dị mkpa ka ị gwa dọkịta gị ka ọ gwa gị ma ọ dị mma ma dị mma maka gị ma tụọ uru na uru. A gaghị eji lumbrokinase mee ihe n'ọnọdụ ọgwụgwọ maka ọnọdụ dịka angina ma ọ bụ strok.
Maka enyemaka n'ibelata ọrịa strok gị, ọ dị mkpa iji jikwaa ọbara mgbali elu na cholesterol, na-eri ihe oriri kwesịrị ekwesị, mmega ahụ mgbe niile, ma zere ịṅụ sịga. Ụfọdụ nnyocha na-enye echiche na ndị na-eri tii tii, tii tii, na Omega-3 acid fatty acids enwere ike ibute ọrịa strok.
Isi mmalite:
> Cao YJ, Zhang X, Wang WH, et al. Oral fibrinogen-depleting agent lumbrokinase maka nkeji nke a na-agwọ ọrịa onchemistry: ihe si na ọtụtụ ndị na-arụ ọrụ, ndị na-enweghị ihe jikọrọ ya na otu, na-achịkwa ikpe. Chin Med J (Engl). 2013 Nov; 126 (21): 4060-5.
> Ji H, Wang L, Bi H, et al. Ntube nke lumbrokinase na nchebe nke cereberal ischemia. Eur J Pharmacol. 2008 Aug 20; 590 (1-3): 281-9.
Jin L, Jin H, Zhang G, Xu G. Ngbanwe na coagulation na anụ ahụ plasminogen activator mgbe a gwọsịrị ụbụrụ ụbụrụ na lumbrokinase. Clinic Hemorheol Microcirc. 2000; 23 (2-4): 213-8.
Kasim M, Kiat AA, Rohman MS, Hanifah Y, Kiat H. Mee ka nsị nke myocardial mejupụta n'ime anụ angina pectoris site na lumbrokinase ọnụ: nchọpụta ụgbọelu. J Altern Gbasara Ọgwụ. 2009 May; 15 (5): 539-44.
Sun H, Ge N, Shao M, Cheng X, Li Y, Li S, Shen J. Lumbrokinase na-adọta ọrịa nchịkwa na-arịa ọrịa shuga site na ịchịkwa mweda afọ nke matrix na streptozotocin na-ebu nje oke. Ọrịa Ọrịa Shuga Na-eme Ọganihu. 2013, 100 (1): 85-95.
Disclaimer: Ihe ọmụma dị na saịtị a bu n'obi maka ebumnuche naanị ma ọ bụghị ihe mgbakwunye maka ndụmọdụ, nyocha ma ọ bụ ọgwụgwọ site na onye dọkịta nyere ikikere. Ekwesighi iji kpuchie ndokwa niile, ọgwụ ọjọọ, ọnọdụ ma ọ bụ mmetụta ọjọọ. Ị ga-achọ nlekọta ahụike ngwa ngwa maka nsogbu ahụike ọbụla ma jụọ dọkịta gị tupu i jiri ọgwụgwọ ọzọ ma ọ bụ gbanwee usoro gị.